Blaine is a given name. Notable people with the name include:
Blaine Bishop (born 1970), American former National Football League safety
Blaine Boyer (born 1981), American Major League Baseball pitcher
Blaine Calkins (born 1968), Canadian politician
Blaine Earon (born 1927), American retired National Football League lineman
Blaine Gabbert (born 1989), American National Football League quarterback
L. Blaine Hammond (born 1952), American test pilot and retired astronaut and US Air Force colonel
Blaine Hardy (born 1987), American baseball player
Blaine Harrison (born 1985), English indie/rock musician
Blaine Higgs (born 1954), Canadian politician
Blaine Johnson (1962-1996), American drag racer
Blaine Kruger (born 1985), Canadian Football League wide receiver
Blaine Lacher (born 1970), Canadian retired National Hockey League goalie
Blaine Larsen (born 1986), American country music singer and songwriter
H. Blaine Lawson (born 1942), American mathematician
Blaine Lindgren (born 1939), American track and field hurdler
Blaine Luetkemeyer (born 1952), U.S. Representative from Missouri
Blaine (cartoonist) (1937–2012), Canadian editorial cartoonist Blaine MacDonald
Blaine McCallister (born 1958), American golfer with five PGA Tour wins
Blaine McElmurry (born 1973), American retired National Football League safety
Blaine Nye (born 1946), American retired National Football League lineman and businessman
Blaine Pedersen, Canadian politician
M. Blaine Peterson (1906-1985), U.S. Representative from Utah
Blaine Saipaia (born 1978), American National Football League player
Blaine Schmidt (born 1963), retired Canadian Football League player
Blaine Scully (born 1988), American rugby union player
Blaine Stoughton (born 1953), Canadian retired National Hockey League player
Blaine Taylor (born 1958), American college basketball player and coach
Blaine Thacker (born 1941), Canadian politician
Blaine Thurier (born 1967), Canadian musician and film producer
Blaine Willenborg (born 1960), American former tennis player
Blaine Wilson (born 1974), American retired gymnast
Fictional characters named Blaine include:
Blaine (Pokémon) (Katsura in the original Japanese version), the name of a gym leader in the Pokémon universe
Blaine Anderson, in the TV series Glee
Blaine the Mono, a psychotic artificial intelligence-controlled monorail locomotive in Stephen King's novels The Wastelands and Wizard and Glass
Blaine (Barbie Doll)
Blaine Edwards, a character portrayed by Damon Wayans in the In Living Color sketch Men on Film
