She first appeared in Mister Miracle vol. 1 #6 (February 1972) and was created by Jack Kirby.
Co-leader of the Female Furies, Bernadeth wields a "fahren-knife" that burns her victims from the inside. As the sister of Darkseid's servant, Desaad, Bernadeth is both notorious and feared by the masses of Apokolips. She was one of the first Furies to be recruited, Bernadeth hated being led by others. When Big Barda left for Earth to be with Mister Miracle, Bernadeth saw this as a way to gain leadership herself. However, Darkseid rewarded Lashina with leadership of the Furies. During a mission to retrieve Glorious Godfrey, Bernadeth betrayed Lashina and left her on Earth. Because of this, Bernadeth was temporarily able to achieve leadership over the Furies. When Lashina returned to Apokolips with the Suicide Squad, she snapped Bernadeth's neck after a long and fierce battle. Darkseid was appalled by the fact that Lashina brought outsiders to Apokolips, so he killed her and resurrected Bernadeth, although he later brought Lashina back to life as well. Afterwards, Bernadeth agreed to share leadership duties.
Recently on Apokalips, she was seen along with the rest of the Furies testing Granny Goodness' newest recruit Precious. After Supergirl's capture, Bernadeth and her teammates were defeated by Wonder Woman and Big Barda.
She appeared in both the Seven Soldiers: Mister Miracle mini-series, and in Hawkgirl.
She made a brief appearance in Countdown to Final Crisis #19, attempting (and failing) to stop Jimmy Olsen and Forager from escaping Apokolips. After they escaped, Bernadeth was confronted by a shadowy Infinity-Man.
Bernadeth appears in Birds of Prey #118, part of the "Dark Side Club" crossover. She creates drugs that helps Granny Goodness brainwash superheroes into fighting at the Dark Side Club arena. She also experiments on cell samples from the club's victims, and thereby was the first to learn that Black Alice was related to Misfit.
After Darkseid had been enslaved by his daughter Grail during The New 52 (a reboot of the DC Comics universe), Bernadeth and the other Female Furies accepted an offer from Big Barda to help defeat Grail as well as to protect Barda's husband, Mister Miracle. Bernadeth participated in the final battle against Grail and Darkseid, which resulted in the pair's defeat. Bernadeth then left for Apokolips with the rest of the Furies, including Barda.
Bernadeth possesses superhuman strength, durability, and endurance. She possesses "faren-knives" which she can telekinetically control that burn their victims from the inside out.
In the Marvel/DC amalgam series Unlimited Access, Bernadeth does not merge with any other villains, but is seen battling the heroes alongside Mad Harriet.
Bernadeth appears in the story "Dig For Fire" in the anthology series Sensation Comics Featuring Wonder Woman. After discovering that Wonder Woman had traveled to Apokolips to save two of her amazon sisters, Lashina, Stompa and Mad Harriet tracked her down. The trio refused to speak peacefully to Wonder Woman, and in the ensuing battle, the heroine was shot in the neck by an explosive dart from Bernadeth and thrown into the fiery pits by Stompa. When the Furies reported back to Darkseid, he was displeased that they had killed her rather than executing her publicly. Wonder Woman, still alive, managed to save her sisters. The Furies once again battled the amazon, though the battle ended when Darkseid killed the two amazons and allowed Wonder Woman to return to Earth.Bernadeth appeared in Justice League Unlimited episode "Alive" voiced by Jennifer Hale. She and the other Furies battled on Granny Goodness' side against the armies led by Virman Vunderbarr and Kanto. Before the battle can commence, Darkseid returns and ends the Civil War.
An alternate version of Bernadeth briefly appears in Justice League: Gods and Monsters. This version closely resembles her appearance from Justice League Unlimited.
In Scribblenauts Unmasked: A DC Comics Adventure, Bernadeth is one of the thousands of characters that can be summoned by the player.