Entrez 9044 | Ensembl ENSG00000095564 | |
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Aliases BTAF1, MOT1, TAF(II)170, TAF172, TAFII170, B-TFIID TATA-box binding protein associated factor 1 External IDs MGI: 2147538 HomoloGene: 31978 GeneCards: BTAF1 | ||
TATA-binding protein-associated factor 172 is a protein that in humans is encoded by the BTAF1 gene.
Contents
Function
Initiation of transcription by RNA polymerase II requires the assistance of TATA box-binding protein (TBP; MIM 600075) and TBP-associated factors, or TAFs (e.g., TAF2B; MIM 604912), in 2 distinct complexes, TFIID and B-TFIID. The TFIID complex is composed of TBP and more than 8 TAFs. However, the majority of TBP is present in the B-TFIID complex, which is composed of TBP and TAFII170, also called TAF172, and has DNA-dependent ATPase activity.[supplied by OMIM]
Interactions
BTAF1 has been shown to interact with TATA binding protein.
References
BTAF1 Wikipedia(Text) CC BY-SA