Species Human Entrez 55589 | Human Mouse Ensembl ENSG00000138756 | |
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Aliases BMP2K, BIKE, HRIHFB2017, BMP2 inducible kinase External IDs MGI: 2155456 HomoloGene: 34134 GeneCards: BMP2K | ||
BMP-2-inducible protein kinase is an enzyme in humans encoded by the BMP2K gene.
Function
This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene.
References
BMP2K Wikipedia(Text) CC BY-SA