Supriya Ghosh (Editor)

BD1067

Updated on
Edit
Like
Comment
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
CAS Number
  
138356-12-4

ChemSpider
  
7972689

3D model (Jmol)
  
Interactive image

PubChem CID
  
9796923

Formula
  
C16H24Cl2N2

Molar mass
  
315.28 g/mol

BD1067

BD1067 or N-[2-(3,4-dichlorophenyl)ethyl]-N-ethyl-1-pyrrolidineethanamine is a selective sigma receptor antagonist, with a reported binding affinity of Ki = 2 ± 0.5 nM for the sigma-1 receptor and greater than 19 times selectivity over the sigma-2 receptor.

Like other sigma receptor antagonists, pretreating Swiss Webster mice with BD1067 significantly attenuates the behavioral toxicity of cocaine.

References

BD1067 Wikipedia


Similar Topics