Kalpana Kalpana (Editor)

BD1060

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CAS Number
  
138356-10-2

ChemSpider
  
8058042

3D model (Jmol)
  
Interactive image

PubChem CID
  
9882367

Formula
  
C14H20Cl2N2

Molar mass
  
287.23 g/mol

BD1060

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BD1060 or N-[2-(3,4-dichlorophenyl)ethyl]-1-pyrrolidineethanamine is a selective sigma receptor antagonist, with a reported binding affinity of Ki = 3 ± 0.1 nM for the sigma-1 receptor and greater than 50 times selectivity over the sigma-2 receptor.

Like other sigma receptor antagonists, pretreating Swiss Webster mice with BD1060 significantly reduces the behavioral toxicity of cocaine.

References

BD1060 Wikipedia