Suvarna Garge (Editor)

BBSome

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The BBSome is a component of the basal body and is involved in formation of the primary cilium. The BBSome is a complex of seven Bardet–Biedl syndrome (BBS) proteins: BBS1, BBS2, BBS4, BBS5, BBS7, BBS8 and BBS9. In addition the BBSome contains the BBIP10 protein.

Contents

BBSome The BBSome

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History

The BBSome was first identified in 2007 by Peter K. Jackson and colleagues.

Assembly

BBSome Full text Advances in the understanding of the BBSome complex

BBSome assembly has been shown to be mediated by a complex containing a further three BBS proteins: BBS6, BBS10 and BBS12. In addition chaperonins of the CCT/TRiC family are involved.

BBSome BBS1 Protein BBS1 and BardetBiedl Syndrome

BBSome A model showing centrosomal complex of BBS4 BBSome complex

BBSome Intrinsic proteinprotein interactions and chaperonin m Openi

BBSome Structural basis for membrane targeting of the BBSome by ARL6

BBSome BBS6 BBS10 and BBS12 form a complex with CCTTRiC family

BBSome The Intraflagellar Transport Protein IFT27 Promotes BBSome Exit from

References

BBSome Wikipedia
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