Entrez 9529 | Ensembl ENSG00000166170 | |
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Aliases BAG5, BAG-5, BCL2 associated athanogene 5 External IDs MGI: 1917619 HomoloGene: 3584 GeneCards: BAG5 |
BAG family molecular chaperone regulator 5 is a protein that in humans is encoded by the BAG5 gene.
The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene.
References
BAG5 Wikipedia(Text) CC BY-SA