EC number 3.4.24.44 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 172306-51-3 BRENDA BRENDA entry KEGG KEGG entry | |
Atrolysin E (EC 3.4.24.44, Crotalus atrox metalloendopeptidase e, hemorrhagic toxin e) is an enzyme. This enzyme catalyses the following chemical reaction
Cleavage of Asn3-Gln, Ser9-His and Ala14-Leu bonds in insulin B chain and Tyr14-Gln and Thr8-Ser in A chain. Cleaves type IV collagen at Ala73-Gln in alpha1(IV) and at Gly7-Leu in alpha2(IV)This endopeptidase is present in the venom of the western diamondback rattlesnake (Crotalus atrox).
References
Atrolysin E Wikipedia(Text) CC BY-SA