Atrolysin B

Atrolysin B (EC 3.4.24.41, Crotalus atrox metalloendopeptidase b, hemorrhagic toxin b, Ht-b) is an enzyme. This enzyme catalyses the following chemical reaction

Cleavage of His⁵-Leu, His¹⁰-Leu, Ala¹⁴-Leu, Tyr¹⁶-Leu and Gly²³-Phe of insulin B chain; identical to the cleavage of insulin B chain by atrolysin C. Also cleaves -Ser bonds in glucagon

This enzyme is present in the western diamondback rattlesnake (Crotalus atrox).