Samiksha Jaiswal (Editor)

Asialoglycoprotein receptor

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Symbol
  
ASGR1

HUGO
  
742

RefSeq
  
NM_001671

Entrez
  
432

OMIM
  
108360

UniProt
  
P07306

The asialoglycoprotein receptors are lectins which bind asialoglycoprotein, glycoproteins from which a sialic acid has been removed to expose galactose residues. The receptors, which are located on liver cells, remove the target glycoproteins from circulation. The asialoglycoprotein receptor has been demonstrated to have high expression on the surface of hepatocytes and several human carcinoma cell lines. Lactobionic acid has been used as a targeting moiety for drug delivery to cells expressing asialoglycoprotein receptors.

References

Asialoglycoprotein receptor Wikipedia


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