Species Human Entrez 410 | Human Mouse Ensembl ENSG00000100299 | |
 | ||
Aliases ARSA, MLD, arylsulfatase A External IDs OMIM: 607574 MGI: 88077 HomoloGene: 20138 GeneCards: ARSA | ||
Arylsulfatase A (or cerebroside-sulfatase) is an enzyme that breaks down sulfatides, namely cerebroside 3-sulfate into cerebroside and sulfate. In humans, arylsulfatase A is encoded by the ARSA gene.
Contents
Pathology
A deficiency is associated with metachromatic leukodystrophy, an autosomal recessive disease.
Enzyme Regulation
Arylsulfatase A is inhibited by phosphate, which forms a covalent bond with the active site 3-oxoalanine.
References
Arylsulfatase A Wikipedia(Text) CC BY-SA