Arylalkyl acylamidase

In enzymology, an arylalkyl acylamidase (EC 3.5.1.76) is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are N-acetylarylalkylamine and H₂O, whereas its two products are arylalkylamine and acetate.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-acetylarylalkylamine amidohydrolase. This enzyme is also called aralkyl acylamidase.