Ram, born in Montevideo, Uruguay, is Jewish. His father Amiram, a former professional soccer player for Betar Jerusalem in the 1950s, is Israeli. After his father was injured he was sent to Uruguay on "shlihut" ("outreach"), and it was there that he met Ram's mother, who is Uruguayan. He has an older brother and a younger sister. They moved to Jerusalem when he was five, which is when he began playing tennis. "It was tough at the beginning because I couldn't speak the language, and was fighting with people in the kindergarten who didn't understand me", said Ram. "My parents decided to send me to the tennis center not long after we arrived."
"I really enjoyed playing tennis, because when I was six or seven years old and winning tournaments it felt good", said Ram. "From when I was 8 or 10 I knew it was going to be a career for me. It's a tennis life so it wasn't so easy. You have to give up many things. When all my friends were playing outside I had to practice. I didn't go to all the school trips. But I was focused from a very young age. I grew up practicing at the Jerusalem tennis center. I spent most of my childhood there, practicing five days a week. I never regretted it and I enjoyed every moment. Now I am reaping the rewards."
Ram was trained by Ronen Moralli at the Israel Tennis Centers in Jerusalem. "My first inspiration was Jo Jo Lizmi, the famous Jerusalem tennis coach, who showed me all the basic techniques. I was with him four or five years and he taught me everything – how to hold the racket, forehand, and backhand. He was very tough." "But the man who really developed my game was Ronen Moralli", says Ram. "He was with me in Jerusalem from when I was 10 years old, but then he moved to Wingate as the national coach." Moralli recalls: "When I worked with Andy at the Jerusalem Tennis Center he was very very energetic and full of passion. His technical abilities weren't as good as the other kids, but he had an understanding of the game. It was something spectacular. He knew when to come to the net, when to stay back. This is something you are born with. Either you have it or you don't. You can teach it, but only up to a certain point, and Andy was born with it."
When he was 15 he was sent to the Wingate Institute, where young Israeli athletes are groomed to become professionals. "It wasn't easy being far away from your family", Ram remembers, "but you know it is going to be your profession and that's what you are going to try to do for life. You practice twice a day and fit in school in between." He became a professional tennis player in 1996, at the age of 16, but did not compete in a Grand Slam tournament until 2001 when he appeared in the Wimbledon doubles with Erlich.
It was at Wingate that he first met Jonathan Erlich, his future doubles partner who was also born in South America. Ram said: "We have known each other for many years. When he was 17 we met at Wingate and ever since we have been practicing together. We grew up together and we complete each other off and on court – the first rule of doubles is communication." He adds: "Yoni and I are very proud of being Israelis. They love us all around the world, and there is a big Jewish community around the world that supports us.... All over the world it is like this. When we go to Beijing even the Chinese Jews cheer for us."
In 2002 Ram was injured, and did not play because he had knee surgery and back surgery. He was on crutches for two months, could not walk, and considered giving up tennis."
In 2003 Ram won the doubles title at the RCA Championship with Croatian Mario Ancic.
With partner Jonathan Erlich, his groundbreaking achievement was their reaching the semifinals of the Wimbledon championships in 2003 as unknown qualifiers. They defeated three seeded opponents en route to the semifinals. In the quarterfinals, in a match in which neither side broke service, Ram and Erlich defeated No. 2 seeded Mark Knowles and Daniel Nestor in straight sets: 7–6, 7–6, 7–6. In the semis, Ram and Erlich – the first Israelis to ever advance to the semifinals in any Grand Slam event – lost to the defending Wimbledon champions, Jonas Bjorkman and Todd Woodbridge.
Ram reached the 2003 Wimbledon mixed doubles final with Anastassia Rodionova of Russia. The couple lost to tennis legend Martina Navratilova and Leander Paes.
Ram felt at that point that he had to choose whether to focus on doubles or singles, as he felt it would be tough to combine the two. He chose to concentrate on doubles.
Ram and Jonathan Erlich then won the Thailand Open in September and the Lyon tournament in October 2003. They also won first place in Indianapolis, Istanbul, India, Rotterdam, and Milan.
Ram competed in the mixed doubles event at the 2004 Roland Garros with partner Petra Mandula of Hungary, and made it as far as the quarterfinals where they lost to Daniela Hantuchova and doubles ace Todd Woodbridge. Ram and Erlich were triumphant yet again in the Lyon International Series tournament in October 2004. They defeated Jonas Bjorkman and Radek Stepanek in the final with a 7–6, 6–2 victory.
In the 2005 Australian Open Ram paired up with Conchita Martinez of Spain in the mixed doubles event. Martinez and Ram pulled off an impressive coup in the quarterfinals, beating top seeds Daniel Nestor and Rennae Stubbs 7–5, 6–7, 7–6. They fell in the semifinals to Aussie pair Scott Draper and Samantha Stosur 7–5, 6–3.
Ram and Erlich won their fourth major tournament in Rotterdam in February 2005, beating Czechs Cyril Suk and Pavel Vizner for the honors. They missed the 2005 Roland Garros grand slam tournament, as Ram's father had died as he was preparing to fly to France.
In August 2005, playing singles he defeated world # 56 Ricardo Mello of Brazil 6–1, 6–4, at the New Haven International.
Ram and Erlich played in the mixed doubles competition in Wimbledon 2005. They faced Kevin Ullyett and Liezel Huber in the quarterfinals, and were eliminated 6–4, 3–6, 8–6. They reached 8th place in the doubles race ranking at the end of 2005, and served as alternates at the Masters Cup in Shanghai.
At the 2007 French Open, Ram, along with his partner, Nathalie Dechy, won the Mixed Doubles competition. Ram and Dechy teamed up together again to compete in the 2007 Wimbledon championships, losing in the third round to 9th-ranked Marcin Matkowski and Cara Black 6–3, 6–4.
At Cincinnati, at the ATP Masters, in August he and Erlich won, upsetting the world # 1 Bryan brothers in the final 4–6, 6–3, 13–11. At the US Open, he played doubles with Erlich, losing in the round of 16 to the eventual winners Simon Aspelin and Julian Simon 5–7, 6–7. In mixed doubles with Nathalie Dechy he made it to the quarter finals.
At the 2008 Australian Open Ram and Erlich won the Men's Doubles Championship in straight sets over Arnaud Clement and Michael Llodra 7–5, 7–6. This was the duo's first Grand Slam win after numerous ATP titles and was also Israel's first ever Grand Slam trophy in Men's Doubles. The duo also won the Masters Series event at Indian Wells, California by defeating the team of Nestor and Zimonic in the finals. After Erlich's injury, Ram was playing with other partners and won indoor titles in Vienna (with Max Mirnyi) and Lyon (with Llodra).
At the 2009 Australian Open Ram and Nathalie Dechy, unseeded at the start of the tournament, defeated two seeded pairs and reached the finals where they lost to another unseeded pair, Sania Mirza and Mahesh Bhupati from India, 3–6, 1–6. Later Ram won Miami Masters tournament with Mirnyi after reaching finals in Indian Wells Masters. Ram has partnered Jonathan Erlich once again at Israel Open ATP Challenger tournament in Ramat Hasharon in May but after losing in the final he announced his decision to keep partnering Mirnyi till the end of 2009 season (with the exception of Davis Cup game against Russia where he will partner Erlich).
He partnered with Julian Knowle for the French Open. They reached the SF, which was the best result for either player at Roland Garros.
Ram has played on the Israel Davis Cup team in 2001–09, going 14–8 through July 2009. In 2007 he won two matches in Israel's 5–0 win over Luxembourg, and he won his doubles matches in Israel's 3–2 wins over Italy and over Chile (in which he and Erlich defeated Olympic Gold Medal winners Gonzalez and Massu). In 2008, Ram and Erlich won their doubles match against Simon Aspelin and Robert Lindstedt in Israel's 3–2 loss to Sweden in the World group, and then Ram partnering Harel Levy defeated the Peruvian duo Mauricio Echazu/Matias Silva on the way to Israel's 4–1 victory, granting Israel a place in the World Group for the next season. In March 2009, partnering Amir Hadad, Ram lost in Malmo to the same Swedish pair he defeated a year earlier, but the Israeli team won 3–2 overall and proceeded to the World Group quarterfinal.
Israel (ranked 8th in the Davis Cup standings, with 5,394 points) hosted heavily favored Russia (which won in both 2002 and 2006, and was the top-ranked country in Davis Cup standings, with 27,897 points) in a Davis Cup quarterfinal tie in July 2009, on indoor hard courts at the Nokia Arena in Tel Aviv. Israel was represented by Ram, Erlich, Dudi Sela, and Harel Levy. Russia's lineup consisted of Marat Safin (# 24 in the world; former world # 1), Igor Andreev (26), Igor Kunitsyn (35), and Mikhail Youzhny (44; former world # 8). The stage was set by Safin, who prior to the tie told the press: "With all due respect, Israel was lucky to get to the quarterfinals." The Israeli team's response was to beat the Russian team in each of their first three matches, thereby winning the tie. Levy, world # 210, beat Russia's top player, Andreev, world # 24, 6–4, 6–2, 4–6, 6–2 in the opening match. Sela (# 33) followed by beating Russian Youzhny 3–6, 6–1, 6–0, 7–5. Israeli captain Eyal Ran likened his players to two fighter jets on court, saying: "I felt as if I had two F-16s out there today, they played amazingly well." The 10,500 spectators were the largest crowd ever for a tennis match in Israel. The next day Ram and Erlich beat Safin and Kunitsyn 6–3, 6–4, 6–7, 4–6, 6–4 in front of a boisterous crowd of over 10,000. "I started to cry like a little boy", said Ram. Even the Saudi Gazette described the doubles match as a "thrilling" win. Captain Ran was carried shoulder-high around the Tel Aviv stadium, as the 10,000-strong crowd applauded. With the tie clinched for Israel, the reverse singles rubbers were "dead", and instead of best-of-five matches, best-of-three sets were played, with the outcomes of little to no importance. Israel wrapped up a 4–1 victory over Russia, as Levy defeated Kunitsyn 6–4, 4–6, 7–6, while Sela retired with a wrist injury while down 3–4 in the first set against Andreev. Ram said: "We have all grown up together since the age of 14. The reason we are in the semis is because we are a united team."
Israel will next face the Spanish Davis Cup team in Marbella, Spain on September 18–20, in Israel's first appearance in the Davis Cup semifinals. Spain won the tie within 2 days. With the tie clinched for Spain, the reverse singles rubbers were "dead", and instead of best-of-five matches, best-of-three sets were played, with the outcomes of little to no importance. Spain wrapped up a 4–1 victory over Israel,
Erlich and Ram represented Israel at the 2004 Summer Olympics in Athens, and reached the quarterfinals. Ranked 8th overall, in the 1st round they defeated Thomas Enqvist and Robin Soderling of Sweden 7–5, 6–3, and then beat Russians Igor Andreev and Nikolay Davydenko in the 2nd round 6–4, 6–1. In the quarterfinals they were defeated by Germans Nicolas Kiefer and Rainer Schuttler in three sets 6–2, 2–6, 2–6.
They also represented Israel at the 2008 Summer Olympics in Beijing, China where they lost to the French team of Arnaud Clement and Michael Llodra in the first round, and at the 2012 Summer Olympics, where they were beaten by the Bryan brothers in the quarter final.Key
Won tournament; or reached Final; Semifinal; Quarter-final; Round 4, 3, 2, 1; competed at a Round Robin stage; lost in Qualification Round; absent from tournament event; played in a Davis Cup - / Fed Cup Zonal Group (with its number indication) or Play-off; won a bronze, silver (F or S) or gold medal at the Olympics; a downgraded Masters Series/1000 tournament (Not a Masters Series); or a tournament that was Not Held in a given year.
To avoid confusion and double counting, these charts are updated either at the conclusion of a tournament, or when the player's participation in the tournament has ended.
Ram was awarded the 2006 accept the inaugural Jerusalem Athlete of the Year award in 2006.
In September 2006, Ram married Shiri, his girlfriend for 10 years, and he lives in Tel Aviv. 
Ram is a fan of the soccer team Beitar Jerusalem.