Anastas is both a surname and a given name. Notable people with the name include:
Surname:
Benjamin Anastas (born 1969), American novelist, journalist and critic born in Gloucester, Massachusetts
Jonathan Anastas, Los Angeles-based advertising executive, musician, cofounded Boston hardcore punk bands
Paul Anastas, the Director of Yale University's Center for Green Chemistry and Green Engineering
Robert Anastas, former hockey coach and teacher at Wayland High School, in Wayland, Massachusetts
Given name:
Anastas Al-Karmali (1866–1947), Lebanese Christian priest, known for his contributions to the field of Arabic linguistics
Anastas Avramidhi-Lakçe (1821–1890), Albanian businessman and benefactor
Anastas Byku (died 1878), Albanian publisher and journalist
Anastas Hanania (1899–1995), Jordanian-Palestinian lawyer, judge, official and diplomat
Anastas Ishirkov (1868–1937), Bulgarian scientist, geographer and ethnographer
Anastas Janullatos (born 1929), Archbishop of Tirana, Durrës and All Albania
Anastas Jovanović (1817–1899), Serbian photographer
Anastas Kristo (born 1985), Albanian footballer
Anastas Kullurioti (1822–1887), Arvanite and Albanian nationalist figure, publisher and writer in Greece
Anastas Mikoyan (1895–1978), Old Bolshevik and Soviet statesman
Anastas Petrov (born 1973), retired Bulgarian footballer and the current manager of Lokomotiv Septemvri