Trisha Shetty (Editor)

Aminothiazole

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Boiling point
  
117 °C

Appearance
  
light yellow crystals

Solubility in water
  
100 kg/m³


2-Aminothiazole is a heterocyclic amine featuring an thiazole core. It can also be considered a cyclic isothiourea. It possesses an odor similar to pyridine and is soluble in water, alcohols and diethyl ether. It is commonly used as a starting point for the synthesis of many compounds including sulfur drugs, biocides, fungicides, dyes and chemical reaction accelerators. 2-Aminothiazole can be used as a thyroid inhibitor in the treatment of hyperthyroidism and has antibacterial activity. Alternatively, its acid tartrate salt can be used. Recent studies using prion-infected neuroblastoma cell lines have suggested that aminothiazole may be used as a therapeutic drug for prion diseases.

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One known use of 2-Aminothiazole in is in the synthesis of Vosaroxin.

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References

Aminothiazole Wikipedia


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