Samiksha Jaiswal (Editor)

Amino acid transporter

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Symbol
  
Aa_trans

InterPro
  
IPR013057

Pfam
  
structures

Pfam
  
PF01490

TCDB
  
2.A.18

PDB
  
RCSB PDB; PDBe; PDBj

An amino acid transporter is a membrane transport protein that transports amino acids. They are mainly of the solute carrier family.

Contents

Families

There are several families that function in amino acid transport, some of these include:

  • TC# 2.A.3 - Amino Acid-Polyamine-Organocation (APC) Superfamily
  • TC# 2.A.18 - Amino Acid/Auxin Permease (AAAP) Family
  • TC# 2.A.23 - Dicarboxylate/Amino Acid:Cation (Na+ or H+) Symporter (DAACS) Family
  • TC# 2.A.26 - Branched Chain Amino Acid:Cation Symporter (LIVCS) Family
  • TC# 2.A.42 - Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family
  • TC# 2.A.78 - Branched Chain Amino Acid Exporter (LIV-E) Family
  • TC# 2.A.95 - 6TMS Neutral Amino Acid Transporter (NAAT) Family
  • TC# 2.A.118 - Basic Amino Acid Antiporter (ArcD) Family
  • TC# 2.A.120 - Putative Amino Acid Permease (PAAP) Family
  • Solute carrier family examples

  • (1) high affinity glutamate and neutral amino acid transporter
  • (3) heavy subunits of heteromeric amino acid transporters
  • (6) Bacterial Leucine Transporter (LeuT)
  • (7) cationic amino acid transporter/glycoprotein-associated
  • (15) proton oligopeptide cotransporter
  • (17) vesicular glutamate transporter
  • (18) vesicular amine transporter
  • (25) some mitochondrial carriers
  • (26) multifunctional anion exchanger
  • (32) vesicular inhibitory amino acid transporter
  • (36) proton-coupled amino acid transporter
  • (38) System A & N, sodium-coupled neutral amino acid transporter
  • VIAAT

    Vesicular inhibitory amino acid transporter (VIAAT) is responsible for the storage of GABA and glycine in neuronal synaptic vesicles.

    Human proteins containing this domain

    ATA2; SLC32A1; SLC36A1; SLC36A2; SLC36A3; SLC36A4; SLC38A1; SLC38A2; SLC38A3; SLC38A4; SLC38A5; SLC38A6;

    References

    Amino acid transporter Wikipedia