Symbol Alpha_RBS RNA type Cis-reg SO 0000233 | Rfam RF00140 Domain(s) Bacteria | |
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The alpha operon ribosome binding site in bacteria is surrounded by this complex pseudoknotted RNA structure. Translation of the mRNA produces 4 ribosomal protein products, one of which (S4) acts as a translational repressor by binding to the nested pseudoknot region. The mechanism of repression is thought to involve a conformational switch in the pseudoknot region and ribosome entrapment.
References
Alpha operon ribosome binding site Wikipedia(Text) CC BY-SA