Samiksha Jaiswal (Editor)

Alpha glucuronidase

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EC number
  
3.2.1.139

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
37259-81-7

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

For beta-glucuronidase, see Beta-glucuronidase

In enzymology, an alpha-glucuronidase (EC 3.2.1.139) is an enzyme that catalyzes the chemical reaction

an alpha-D-glucuronoside + H2O an alcohol + D-glucuronate

Thus, the two substrates of this enzyme are alpha-D-glucuronoside and H2O, whereas its two products are alcohol and D-glucuronate.

This enzyme belongs to the family of hydrolases, to be specific those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is alpha-D-glucosiduronate glucuronohydrolase. This enzyme is also called alpha-glucosiduronase.

Structural studies

As of late 2007, 13 structures have been solved for this class of enzymes, with PDB accession codes 1GQI, 1GQJ, 1GQK, 1GQL, 1H41, 1K9D, 1K9E, 1K9F, 1L8N, 1MQP, 1MQQ, 1MQR, and 1VJT.

References

Alpha-glucuronidase Wikipedia