EC number 3.2.1.24 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 9025-42-7 BRENDA BRENDA entry KEGG KEGG entry | |
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alpha-Mannosidase (EC 3.2.1.24, alpha-D-mannosidase, p-nitrophenyl-alpha-mannosidase, alpha-D-mannopyranosidase, 1,2-alpha-mannosidase, 1,2-alpha-D-mannosidase, exo-alpha-mannosidase) is an enzyme involved in the cleavage of the alpha form of mannose. Its systematic name is alpha-D-mannoside mannohydrolase.
Contents
Isozymes
Humans express the following three alpha-mannosidase isozymes:
Applications
It can be utilized in experiments that determine the effects of the presence or absence of mannose on specific molecules, such as recombinant proteins that are used in vaccine development.
Pathology
A deficiency can lead to alpha-mannosidosis.
References
Alpha-Mannosidase Wikipedia(Text) CC BY-SA