Alky-lysophospholipids (ALP) are synthetic analogues of lysophosphatidylcholines (LPC), also called lysolecithins. They are synthesized by replacing the acyl-group within the LPC with an alkyl-group. They are in contrast to LPC metabolically very stable., They have anti-neoplastic (“anti-cancer”) effects. and they are immune modulators. Their anti-tumor efficiency is due to influence on signal pathways of the cell, causing apoptosis. It has highly selective, sparing healthy cells. Several like Edelfosine, Miltefosine and Perifosine are under research and development as drugs against cancer and other diseases.
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Alkyl-lysophospholipids Wikipedia(Text) CC BY-SA