Alizai is a Pashtun tribe indigenous to southern Afghanistan and Northern and Southern Pakistan. It belongs to the Panjpai confederation of the larger Durrani tribe of Ahmad Shah Durrani. Sardar Ahmed Nawaz Khan Alizai Advocate is the chieftain of Alizai tribe in Balochistan.
The Alizai tribe mostly reside in Khyber Pakhtunkhwa and also in the tribal area's in Pakistan and they also reside in the Loy Kandahar region of southern Afghanistan. They are concentrated around Helmand and Farah provinces.
In 2007, Alizai tribesmen in the village of Musa Qala in Helmand province united under Mullah Abdul Salam fought alongside the Taliban. Mullah Abdul Salam later agreed to change sides and was appointed by President Hamid Karzai as the governor of Musa Qala district.