Acylcarnitine hydrolase

In enzymology, an acylcarnitine hydrolase (EC 3.1.1.28) is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are O-acylcarnitine and H₂O, whereas its two products are fatty acid and L-carnitine.

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is O-acylcarnitine acylhydrolase. Other names in common use include high activity acylcarnitine hydrolase, HACH, carnitine ester hydrolase, palmitoylcarnitine hydrolase, palmitoyl-L-carnitine hydrolase, long-chain acyl-L-carnitine hydrolase, and palmitoyl carnitine hydrolase.