EC number 3.1.2.20 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 37270-64-7 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, an acyl-CoA hydrolase (EC 3.1.2.20) is an enzyme that catalyzes the chemical reaction
acyl-CoA + H2OThus, the two substrates of this enzyme are acyl-CoA and H2O, whereas its two products are CoA and carboxylate.
This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is acyl-CoA hydrolase. Other names in common use include acyl coenzyme A thioesterase, acyl-CoA thioesterase, acyl coenzyme A hydrolase, thioesterase B, thioesterase II, and acyl-CoA thioesterase.
Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1Y7U and 2GVH.
References
Acyl-CoA hydrolase Wikipedia(Text) CC BY-SA