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Acetic formic anhydride

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Acetic formic anhydride Synthesis of acetic formic anhydride PrepChemcom

Acetic formic anhydride is an organic compound with the chemical formula C
3
H
4
O
3
and a structural formula of H
3
C
-(C=O)-O-(C=O)H. It can be viewed as the mixed anhydride of acetic acid and formic acid.

Contents

Acetic formic anhydride Acetic formic anhydride Exporter Acetic formic anhydride

Preparation

Acetic formic anhydride 212 Part 2 Reactions of Carboxylic Acid Derivatives Wade 7th

Acetic Formic anhydride can be produced by reacting sodium formate with acetyl chloride in anhydrous diethyl ether between 23–27 °C.

Applications

Acetic formic anhydride Synthesis of acetic formic anhydride PrepChemcom

Acetic formic anhydride is a formylation agent for amines, amino acids, and alcohols. It is also a starting material for other compounds such as formyl fluoride.

An example of Acetic formic anhydride being used was in the synthesis of Quazodine (U.S. Patent 3,248,292).

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References

Acetic formic anhydride Wikipedia