Harman Patil

ATP5D

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Aliases  ATP5D
Human  Mouse
Ensembl  ENSG00000099624
Species  Human
Entrez  513
ATP5D
External IDs  MGI: 1913293 HomoloGene: 37514 GeneCards: ATP5D

ATP synthase subunit delta, mitochondrial is an enzyme that in humans is encoded by the ATP5D gene.

Function

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the delta subunit of the catalytic core. Alternatively spliced transcript variants encoding the same isoform have been identified.

References

ATP5D Wikipedia


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