Harman Patil

ASF1B

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Species  Human
Entrez  55723
Human  Mouse
Ensembl  ENSG00000105011
ASF1B
Aliases  ASF1B, CIA-II, anti-silencing function 1B histone chaperone
External IDs  MGI: 1914179 HomoloGene: 56797 GeneCards: ASF1B

Histone chaperone ASF1B is a protein that in humans is encoded by the ASF1B gene.

Contents

Function

This gene encodes a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring a constant supply of histones at sites of nucleosome assembly.

Interactions

ASF1B has been shown to interact with TLK2, CHAF1B, TLK1 and CHAF1A.

References

ASF1B Wikipedia


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