Species Human Entrez 25842 | Human Mouse Ensembl ENSG00000111875 | |
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Aliases ASF1A, CGI-98, CIA, HSPC146, anti-silencing function 1A histone chaperone External IDs MGI: 1913653 HomoloGene: 8528 GeneCards: ASF1A | ||
Histone chaperone ASF1A is a protein that in humans is encoded by the ASF1A gene.
Contents
Function
This gene encodes a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The protein is a key component of a histone donor complex that functions in nucleosome assembly. It interacts with histones H3 and H4, and functions together with a chromatin assembly factor during DNA replication and repair.
Interactions
ASF1A has been shown to interact with TLK1, TLK2, CHAF1B and CHAF1A.
References
ASF1A Wikipedia(Text) CC BY-SA