Species Human Entrez 10095 | Human Mouse Ensembl ENSG00000130429 | |
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Aliases ARPC1B, ARC41, p40-ARC, p41-ARC, actin related protein 2/3 complex subunit 1B External IDs MGI: 1343142 HomoloGene: 4179 GeneCards: ARPC1B | ||
Actin-related protein 2/3 complex subunit 1B is a protein that in humans is encoded by the ARPC1B gene.
Contents
Function
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages.
Interactions
ARPC1B has been shown to interact with PAK1.