Suvarna Garge

ARL1

Updated on
Share on FacebookTweet on TwitterShare on LinkedIn
Species  Human
Entrez  400
Human  Mouse
Ensembl  ENSG00000120805
ARL1
Aliases  ARL1, ARFL1, ADP ribosylation factor like GTPase 1
External IDs  MGI: 99436 HomoloGene: 20319 GeneCards: ARL1

ADP-ribosylation factor-like protein 1 is a protein that in humans is encoded by the ARL1 gene.

Contents

Function

The protein encoded by this gene belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner.

Interactions

ARL1 has been shown to interact with GOLGA4 and GOLGA1.

References

ARL1 Wikipedia


Similar Topics
ARL11
Wu Dang (film)
Peter McColgan
Topics