Entrez 50650 | Ensembl ENSG00000163947 | |
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Aliases ARHGEF3, GEF3, STA3, XPLN, Rho guanine nucleotide exchange factor 3 External IDs MGI: 1918954 HomoloGene: 41329 GeneCards: ARHGEF3 |
Rho guanine nucleotide exchange factor (GEF) 3, also known as ARHGEF3, is a human gene.
Contents
Function
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein-coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. This protein is similar to the NET1A protein.
Interactions
ARHGEF3 has been shown to interact with RHOA and RHOB.
References
ARHGEF3 Wikipedia(Text) CC BY-SA