|Aliases ARHGEF3, GEF3, STA3, XPLN, Rho guanine nucleotide exchange factor 3|
External IDs MGI: 1918954 HomoloGene: 41329 GeneCards: ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3, also known as ARHGEF3, is a human gene.
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein-coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. This protein is similar to the NET1A protein.
ARHGEF3 has been shown to interact with RHOA and RHOB.