Entrez 9181 | Ensembl ENSG00000116584 | |
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Aliases ARHGEF2, GEF, GEF-H1, GEFH1, LFP40, P40, Rho/Rac guanine nucleotide exchange factor 2 External IDs MGI: 103264 HomoloGene: 3468 GeneCards: ARHGEF2 | ||
Rho guanine nucleotide exchange factor 2 is a protein that in humans is encoded by the ARHGEF2 gene.
Contents
Function
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein-coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals.
Interactions
ARHGEF2 has been shown to interact with PAK1.
References
ARHGEF2 Wikipedia(Text) CC BY-SA