Entrez 394 | Ensembl ENSG00000100852 | |
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Aliases ARHGAP5, GFI2, RhoGAP5, p190-B, p190BRhoGAP, Rho GTPase activating protein 5 External IDs MGI: 1332637 HomoloGene: 907 GeneCards: ARHGAP5 | ||
Function
Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family that may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this gene.
Interactions
ARHGAP5 has been shown to interact with Rnd1, Rnd2, Rnd3 and RHOA.
References
ARHGAP5 Wikipedia(Text) CC BY-SA