Trisha Shetty

ARHGAP5

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Species  Human
Entrez  394
Human  Mouse
Ensembl  ENSG00000100852
ARHGAP5
Aliases  ARHGAP5, GFI2, RhoGAP5, p190-B, p190BRhoGAP, Rho GTPase activating protein 5
External IDs  MGI: 1332637 HomoloGene: 907 GeneCards: ARHGAP5

Rho GTPase-activating protein 5 is an enzyme that in humans is encoded by the ARHGAP5 gene.

Contents

Function

Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family that may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this gene.

Interactions

ARHGAP5 has been shown to interact with Rnd1, Rnd2, Rnd3 and RHOA.

References

ARHGAP5 Wikipedia


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