Species Human Entrez 394 | Human Mouse Ensembl ENSG00000100852 | |
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Aliases ARHGAP5, GFI2, RhoGAP5, p190-B, p190BRhoGAP, Rho GTPase activating protein 5 External IDs MGI: 1332637 HomoloGene: 907 GeneCards: ARHGAP5 | ||
Rho GTPase-activating protein 5 is an enzyme that in humans is encoded by the ARHGAP5 gene.
Contents
Function
Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family that may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this gene.
Interactions
ARHGAP5 has been shown to interact with Rnd1, Rnd2, Rnd3 and RHOA.
References
ARHGAP5 Wikipedia(Text) CC BY-SA