| AP3B1, ADTB3, ADTB3A, HPS, HPS2, PE, adaptor related protein complex 3 beta 1 subunit|
MGI: 1333879 HomoloGene: 68125 GeneCards: AP3B1
AP-3 complex subunit beta-1 is a protein that in humans is encoded by the AP3B1 gene.
This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 2.
AP3B1 has been shown to interact with AP3S2.