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ALX1

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Species  Human
Entrez  8092
Human  Mouse
Ensembl  ENSG00000180318
ALX1
Aliases  ALX1, CART1, FND3, HEL23, ALX homeobox 1
External IDs  MGI: 104621 HomoloGene: 5075 GeneCards: ALX1

ALX homeobox protein 1 is a protein that in humans is encoded by the ALX1 gene.

Contents

Function

The specific function of this gene has yet to be determined in humans; however, in rodents, it is necessary for survival of the forebrain mesenchyme and may also be involved in development of the cervix. Mutations in the mouse gene lead to neural tube defects such as acrania and meroanencephaly.

In Darwin's finches, inhabiting the Galapagos islands, ALX1 has been linked to the diversity of beak shapes.

Interactions

ALX1 has been shown to interact with IPO13.

References

ALX1 Wikipedia


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