Species Human Entrez 8092 | Human Mouse Ensembl ENSG00000180318 | |
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Aliases ALX1, CART1, FND3, HEL23, ALX homeobox 1 External IDs MGI: 104621 HomoloGene: 5075 GeneCards: ALX1 | ||
ALX homeobox protein 1 is a protein that in humans is encoded by the ALX1 gene.
Contents
Function
The specific function of this gene has yet to be determined in humans; however, in rodents, it is necessary for survival of the forebrain mesenchyme and may also be involved in development of the cervix. Mutations in the mouse gene lead to neural tube defects such as acrania and meroanencephaly.
In Darwin's finches, inhabiting the Galapagos islands, ALX1 has been linked to the diversity of beak shapes.
Interactions
ALX1 has been shown to interact with IPO13.
References
ALX1 Wikipedia(Text) CC BY-SA