Trisha Shetty (Editor)

ALG3

Updated on
Edit
Like
Comment
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
Species
  
Human

Entrez
  
10195

Human
  
Mouse

Ensembl
  
ENSG00000214160

Aliases
  
ALG3, CDG1D, CDGS4, D16Ertd36e, NOT56L, Not56, CDGS6, not, alpha-1,3- mannosyltransferase

External IDs
  
MGI: 1098592 HomoloGene: 4228 GeneCards: ALG3

Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase is an enzyme that in humans is encoded by the ALG3 gene.

This gene encodes a member of the ALG3 family. The encoded protein catalyses the addition of the first dol-P-Man derived mannose in an alpha 1,3 linkage to Man5GlcNAc2-PP-Dol. Defects in this gene have been associated with congenital disorder of glycosylation type Id (CDG-Id) characterized by abnormal N-glycosylation.

References

ALG3 Wikipedia