ADCY8

Function

Adenylyl cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (R_s and R_i) interact with G proteins (G_s and G_i) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase.