Suvarna Garge


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CAS Number  1445583-51-6
ChemSpider  29763706
Formula  C21H23FN4O2
PubChem CID  70969086
UNII  05235E1S2O
Molar mass  382.43 g/mol
ADB-FUBINACA httpsuploadwikimediaorgwikipediacommonsthu
Legal status  CA: Schedule II DE: Anlage II (Prohibited)

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ADB-FUBINACA is a designer drug identified in synthetic cannabis blends in Japan in 2013. The (S) enantiomer of ADB-FUBINACA is claimed in Pfizer patent WO 2009/106982 and has been reported to be a potent agonist of the CB1 receptor and CB2 receptor with an EC50 value of 1.2 nM and 3.5 nM respectively. ADB-FUBINACA features a carboxamide group at the 3-indazole position, like SDB-001 and STS-135. ADB-FUBINACA appears to be the product of rational drug design, since it differs from AB-FUBINACA only by the replacement of the isopropyl group with a tert-butyl group.


An analogue of ADB-FUBINACA, ADSB-FUB-187, containing a more functionalized carboxamide substituent was recently reported.

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Side effects

One death through coronary arterial thrombosis has been linked to ADB-FUBINACA intoxication.



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