Species Human Entrez 51225 | Human Mouse Ensembl ENSG00000108798 | |
 | ||
Aliases ABI3, NESH, SSH3BP3, ABI family member 3 External IDs MGI: 1913860 HomoloGene: 9505 GeneCards: ABI3 | ||
ABI gene family member 3 (ABI3) also known as new molecule including SH3 (Nesh) is a protein that in humans is encoded by the ABI3 gene.
Function
This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinases.
References
ABI gene family member 3 Wikipedia(Text) CC BY-SA