Supriya Ghosh (Editor)

8 Phenyltheophylline

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Covid-19
ATC code  None
PubChem CID  1922
ChEMBL  CHEMBL62350
Molar mass  256.259 g/mol
CAS Number  961-45-5
ChemSpider  1846
Formula  C13H12N4O2
8-Phenyltheophylline httpsuploadwikimediaorgwikipediacommonsthu

8-Phenyltheophylline (8-phenyl-1,3-dimethylxanthine, 8-PT) is a drug derived from the xanthine family which acts as a potent and selective antagonist for the adenosine receptors A1 and A2A, but unlike other xanthine derivatives has virtually no activity as a phosphodiesterase inhibitor. It has stimulant effects in animals with similar potency to caffeine. Coincidentally 8-phenyltheophylline has also been found to be a potent and selective inhibitor of the liver enzyme CYP1A2 which makes it likely to cause interactions with other drugs which are normally metabolised by CYP1A2.

References

8-Phenyltheophylline Wikipedia


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