Harman Patil (Editor)

60S ribosomal protein L11

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Species  Human
Entrez  6135
Human  Mouse
Ensembl  ENSG00000142676
60S ribosomal protein L11 wwwnaturecomnmjournalv17n8imagesnm2392F4jpg

Aliases  RPL11, DBA7, GIG34, L11, ribosomal protein L11
External IDs  MGI: 1914275 HomoloGene: 37376 GeneCards: RPL11

60S ribosomal protein L11 is a protein that in humans is encoded by the RPL11 gene.



Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L5P family of ribosomal proteins. It is located in the cytoplasm. The protein probably associates with the 5S rRNA. Alternative splice variants encoding different isoforms may exist, but they have not been fully characterized. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.


RPL11 has been shown to interact with:

  • BLMH,
  • Mdm2,
  • P16,
  • P53, and
  • Promyelocytic leukemia protein
  • References

    60S ribosomal protein L11 Wikipedia