Harman Patil (Editor)

5 APDI

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Covid-19
Routes of administration  Oral
CAS Number  13396-94-6
Molar mass  175.27 g/mol
ATC code  none
PubChem CID  192600
5-APDI
Legal status  CA: Schedule III UK: Class B
Synonyms  1-(5-indanyl)-2-aminopropane

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5-(2-Aminopropyl)-2,3-dihydro-1H-indene (5-APDI), also known as indanylaminopropane (IAP), IAP (psychedelic), 2-API(2-aminopropylindane), indanametamine, and, incorrectly, as indanylamphetamine, is an entactogen and psychedelic drug of the amphetamine family. It has been sold by online vendors through the Internet and has been encountered as a designer drug since 2003, but its popularity and availability has diminished in recent years.

5-APDI acts as a potent and weakly selective serotonin releasing agent (SSRA) with IC50 values of 82 nM, 1,848 nM, and 849 nM for inhibiting the reuptake of serotonin, dopamine, and norepinephrine, respectively. It fully substitutes for MBDB but not amphetamine in trained animals, though it does produce disruption for the latter at high doses.

5-APDI has been classified as a class B drug under the Misuse of Drugs Act 1971 since 10 June 2014.

References

5-APDI Wikipedia


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