Trisha Shetty (Editor)

5,10 Methenyltetrahydrofolate

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Covid-19
Formula  C20H213N7O6
Molar mass  455.42 g/mol
5,10-Methenyltetrahydrofolate httpsuploadwikimediaorgwikipediacommonsthu

Gene music using protein sequence of mthfs 5 10 methenyltetrahydrofolate synthetase 5 formyltetra


5,10-Methenyltetrahydrofolate (5,10-CH=THF) is a form of tetrahydrofolate that is an intermediate in metabolism. 5,10-CH=THF is a coenzyme that accepts and donates methenyl (CH=) groups.

Contents

It is produced from 5,10-methylenetetrahydrofolate by either a NAD+ dependent methylenetetrahydrofolate dehydrogenase, or a NADP+ dependent dehydrogense. It can also be produced as an intermediate in histidine catabolism, by formiminotransferase cyclodeaminase, from 5-formiminotetrahydrofolate.

5,10-CH=THF is a substrate for methenyltetrahydrofolate cyclohydrolase, which converts it into 10-formyltetrahydrofolate.

Interactive pathway map

Click on genes, proteins and metabolites below to link to respective articles.

References

5,10-Methenyltetrahydrofolate Wikipedia


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