Supriya Ghosh (Editor)

4 nitrophenylphosphatase

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EC number
  
3.1.3.41

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
9073-68-1

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a 4-nitrophenylphosphatase (EC 3.1.3.41) is an enzyme that catalyzes the chemical reaction

4-nitrophenyl phosphate + H2O 4-nitrophenol + phosphate

Thus, the two substrates of this enzyme are 4-nitrophenyl phosphate and H2O, whereas its two products are 4-nitrophenol and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is 4-nitrophenylphosphate phosphohydrolase. Other names in common use include nitrophenyl phosphatase, p-nitrophenylphosphatase, para-nitrophenyl phosphatase, K-pNPPase, NPPase, PNPPase, Ecto-p-nitrophenyl phosphatase, and p-nitrophenylphosphate phosphohydrolase. This enzyme participates in gamma-hexachlorocyclohexane degradation.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code PDB: 1VJR​.

References

4-nitrophenylphosphatase Wikipedia