EC number 3.1.2.23 ExPASy NiceZyme view | CAS number 141583-19-9 | |
In enzymology, a 4-hydroxybenzoyl-CoA thioesterase (EC 3.1.2.23) is an enzyme that catalyzes the chemical reaction
4-hydroxybenzoyl-CoA + H2O
Thus, the two substrates of this enzyme are 4-hydroxybenzoyl-CoA and H2O, whereas its two products are 4-hydroxybenzoate and CoA.
This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is 4-hydroxybenzoyl-CoA hydrolase. This enzyme participates in 2,4-dichlorobenzoate degradation.
Structural studies
As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes 1HN1, 1LO7, 1LO8, 1LO9, 1Q4S, 1Q4T, and 1Q4U.
References
4-hydroxybenzoyl-CoA thioesterase Wikipedia(Text) CC BY-SA