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4 hydroxybenzoyl CoA thioesterase

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EC number
  
3.1.2.23

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
141583-19-9

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a 4-hydroxybenzoyl-CoA thioesterase (EC 3.1.2.23) is an enzyme that catalyzes the chemical reaction

4-hydroxybenzoyl-CoA + H2O 4-hydroxybenzoate + CoA

Thus, the two substrates of this enzyme are 4-hydroxybenzoyl-CoA and H2O, whereas its two products are 4-hydroxybenzoate and CoA.

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is 4-hydroxybenzoyl-CoA hydrolase. This enzyme participates in 2,4-dichlorobenzoate degradation.

Structural studies

As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes 1HN1, 1LO7, 1LO8, 1LO9, 1Q4S, 1Q4T, and 1Q4U.

References

4-hydroxybenzoyl-CoA thioesterase Wikipedia