4 chlorobenzoyl CoA dehalogenase

In enzymology, a 4-chlorobenzoyl-CoA dehalogenase (EC 3.8.1.7) is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are 4-chlorobenzoyl-CoA and H₂O, whereas its two products are 4-hydroxybenzoyl CoA and chloride.

This enzyme belongs to the family of hydrolases, specifically those acting on halide bonds in carbon-halide compounds. The systematic name of this enzyme class is 4-chlorobenzoyl CoA chlorohydrolase. This enzyme participates in 2,4-dichlorobenzoate degradation.