Suvarna Garge (Editor)

4 chlorobenzoate dehalogenase

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EC number
  
3.8.1.6

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
94047-11-7

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a 4-chlorobenzoate dehalogenase (EC 3.8.1.6) is an enzyme that catalyzes the chemical reaction

4-chlorobenzoate + H2O 4-hydroxybenzoate + chloride

Thus, the two substrates of this enzyme are 4-chlorobenzoate and H2O, whereas its two products are 4-hydroxybenzoate and chloride.

This enzyme belongs to the family of hydrolases, specifically those acting on halide bonds in carbon-halide compounds. The systematic name of this enzyme class is 4-chlorobenzoate chlorohydrolase. This enzyme is also called halobenzoate dehalogenase.

Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 1BVQ, 1JXZ, and 1NZY.

References

4-chlorobenzoate dehalogenase Wikipedia