Suvarna Garge

4 HO MPMI

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CAS Number  250672-65-2
ChemSpider  8641815
3D model (Jmol)  Interactive image
PubChem CID  10466404
Formula  C14H17N2O
Molar mass  229.297 g/mol
4-HO-MPMI

4-HO-MPMI (also known as 4-Hydroxy-N-methyl-(α,N-trimethylene)tryptamine or lucigenol) is a tryptamine derivative that is a psychedelic drug. It was developed by the team led by David Nichols from Purdue University in the late 1990s. This compound produces hallucinogen-appropriate responding in animal tests with a similar potency to the amphetamine-derived psychedelic DOI, and has two enantiomers, with only the (R)-enantiomer being active.

The binding affinity for 5-HT2A receptor is 13 ± 2 nM (Ki [125I]DOI). It is reported at doses starting at 0.5 mg and 1.0-1.5 mg seem to be psychedelic doses. The duration it is reported between six and eight hours. The effects, still not too documented, are OEV/CEV, sedation and anxiety.

References

4-HO-MPMI Wikipedia


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