Samiksha Jaiswal (Editor)

4 Fluorobenzoic acid

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Density  1.479 g/cm³
Appearance  white solid
4-Fluorobenzoic acid wwwsigmaaldrichcomcontentdamsigmaaldrichstr

4-Fluorobenzoic acid (p-fluorobenzoic acid) is an organic compound with the formula C7H5FO2. This colourless solid is a derivative of benzoic acid carboxylic acid. It is a synthetic intermediate.

Preparation

4-Fluorobenzoic acid is commercially available. It may be prepared via the Schiemann reaction, in which a 4-aminobenzoic acid, protected as the ethyl ester, is diazotised and then fluoride introduced using tetrafluoroborate. Hydrolysis of the ester converts it back to the free acid.

4-Fluorobenzoic acid has been observed to form by the aerobic biotransformation of 4-fluorocinnamic acid.

References

4-Fluorobenzoic acid Wikipedia


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