Trisha Shetty (Editor)

4 Dimethylaminophenol

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Formula
  
C8H11NO

Boiling point
  
165 °C

Molar mass
  
137.179 g/mol

4-Dimethylaminophenol wwwchemspidercomImagesHandlerashxid20816ampw2

4-Dimethylaminophenol (abbreviated in medical practice as DMAP) is an aromatic compound containing both phenol and amine functional groups. It has the molecular formula C8H11NO.

Uses

4-Dimethylaminophenol has been used as an antidote for cyanide poisoning. It has also been shown to be effective in treating hydrogen sulfide toxicity.

It works by generating methemoglobin.

This is suitable as an emergency treatment only; treatment must be followed up with sodium thiosulfate or cobalamin.

In an animal model, it has shown effectiveness when given intramuscularly. Though, intramuscular injection should be avoid due to the probability of muscular necrosis after injection. Intravenous injection is recommended in a dose of 250 mg.

References

4-Dimethylaminophenol Wikipedia